发明名称 |
Substituted benzyloxy-carbonylguanidines, a process for their preparation, their use as a medicament or diagnostic, and a medicament containing them |
摘要 |
There are described compounds of the formula I in which the substituents R(1) to R(7) and X have the meanings shown in the claims, and their pharmaceutically tolerable salts. These are effective inhibitors of the cellular sodium proton antiporter (Na+/H+ exchanger). They are therefore outstandingly suitable for the treatment of all diseases which can be attributed to increased Na+/H+ exchange.
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申请公布号 |
US6022899(A) |
申请公布日期 |
2000.02.08 |
申请号 |
US19980005163 |
申请日期 |
1998.01.09 |
申请人 |
HOECHST AKTIENGESELLSCHAFT |
发明人 |
KLEEMANN, HEINZ-WERNER;BRENDEL, JOACHIM;SCHWARK, JAN-ROBERT;WEICHERT, ANDREAS;LANG, HANS-JOCHEN;ALBUS, UDO;SCHOLZ, WOLFGANG |
分类号 |
C07D215/20;A61K9/06;A61K9/10;A61K31/155;A61K31/17;A61K31/175;A61K31/18;A61K31/27;A61K31/275;A61K31/44;A61K31/4406;A61K31/4418;A61K31/47;A61K31/475;A61K35/00;A61P1/16;A61P3/08;A61P9/00;A61P9/06;A61P9/08;A61P9/10;A61P13/02;A61P15/00;A61P35/00;A61P43/00;C07C279/10;C07C279/24;C07C317/22;C07C317/32;C07C317/46;C07D213/30;C07D215/14;G01N33/574;G01N33/94;(IPC1-7):A61K31/17;C07C275/04 |
主分类号 |
C07D215/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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