Tricyclic tetrahydroquinoline derivatives and tricyclic tetrahydroquinoline combinatorial libraries

摘要

he present invention relates to a combinatorial library of two or more tricyclic tetrahydroquinoline compounds of the formula 1; Where the substituents are defined in the specification. Also claimed is a method for the preparation of a library of two or more tricyclic tetrahydroquinoline compounds by reacting a resin bound aniline with an aldehyde to obtain an imine and reacting in the presence of an acid the imine of the previous step with a dienophile to yield a tetrahydroquinoline.