发明名称 |
GENOTYPING THE HUMAN PHENOL SULFOTRANSFERASE 2 GENE (STP2) |
摘要 |
Genetic polymorphisms are identified in the human STP2 gene that alter STP2-dependent drug metabolism. Nucleic acids comprising the polymorphic sequences are used to screen patients for altered metabolism for STP2 substrates, potential drug-drug interactions, and adverse/side effects, as well as diseases that result from environmental or occupational exposure to toxins. The nucleic acids are used to establish animal, cell and in vitro models for drug metabolism.
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申请公布号 |
WO9964630(A1) |
申请公布日期 |
1999.12.16 |
申请号 |
WO1999US13094 |
申请日期 |
1999.06.09 |
申请人 |
AXYS PHARMACEUTICALS, INC. |
发明人 |
GUIDA, MARCO;KURTH, JANICE |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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主权项 |
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