发明名称 PHYSICAL FORM OF (R)-7-ACETYL-5-(4-AMINOPHENYL)-8,9- DIHYDRO-8-METHYL-7H-1,3-DIOXOLO [4,5-h]-[2,3]- BENZODIAZEPINE, METHOD OF PREPARING THEREOF, AND PHARMACEUTICAL COMPOSITION
摘要 FIELD: pharmaceutical industry. SUBSTANCE: described is physical form of (R)-- acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3- dioxolo [4,5-h] -[2,3] -benzodiazepine having powder roentgenogram with d parameters at 12.78, 9.48, 8.99, 8.64, 8.23, 6.39, 6.27, 5.73, 4.01 and 3.96A. Said physical form has favorable properties suitable for production of pharmaceutical product useful as AMPA antagonist. EFFECT: improved properties of the pharmaceutical composition. 5 cl, 24 ex, 1 tbl
申请公布号 RU2142465(C1) 申请公布日期 1999.12.10
申请号 RU19950114550 申请日期 1995.08.30
申请人 EHLI LILLI EHND KOMPANI 发明人 BENDZHAMIN EHLAN ANDERSON;MARVIN MARTIN KHENSEN;DZHEFFRI TOMAS VICHENTSI;DEHVID LI VEHRI;MILTON DZHOZEF ZHMIZHEVSKI;EHDVARD GRANT GROLO
分类号 A61K31/55;A61K31/551;C07D317/58;C07D491/04;C07D491/056;C07D493/04;(IPC1-7):C07D491/056 主分类号 A61K31/55
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