发明名称 Methods of diagnosis by detecting polymorphisms in the TGF- beta 1 promoter
摘要 A method of diagnosis comprises determining genotype of a TGF- beta 1 promoter-specific polmorphisms that have been identified are at positions -800bp and -509bp. The genotype determined is then used to assess predisposition or susceptibility to a number of diseases: osteoporosis, atherosclerosis, cancer and immune disorders.
申请公布号 US5998137(A) 申请公布日期 1999.12.07
申请号 US19970784386 申请日期 1997.01.17
申请人 GRAINGER, DAVID J.;SPECTOR, TIMOTHY D.;HEATHCOTE, KIRSTEN 发明人 GRAINGER, DAVID J.;SPECTOR, TIMOTHY D.;HEATHCOTE, KIRSTEN
分类号 G01N33/50;A61K31/00;A61K38/22;A61P9/00;A61P9/10;A61P19/00;A61P19/10;A61P35/00;A61P37/00;C12N15/09;C12Q1/68;(IPC1-7):C12Q1/68;C07H21/04 主分类号 G01N33/50
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