摘要 |
Methods and compositions utilizing a compound represented by formula (III), wherein R is chosen from -OH, -P(O)(OH)2 and -SO3H, or a pharmaceutically acceptable salt thereof, for the treatment of psychoses in humans are disclosed. Compounds of formula (III) exhibit fewer side effects than risperidone, a lessened liability toward drug-drug interactions than risperidone and a more predictable dosing regimen than risperidone. The compounds of the invention are also useful for the treatment of emesis and withdrawal syndromes.
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