发明名称 (+)-HYDROXYRISPERIDONE COMPOSITIONS AND METHODS
摘要 Methods and compositions utilizing a compound represented by formula (III), wherein R is chosen from -OH, -P(O)(OH)2 and -SO3H, or a pharmaceutically acceptable salt thereof, for the treatment of psychoses in humans are disclosed. Compounds of formula (III) exhibit fewer side effects than risperidone, a lessened liability toward drug-drug interactions than risperidone and a more predictable dosing regimen than risperidone. The compounds of the invention are also useful for the treatment of emesis and withdrawal syndromes.
申请公布号 WO9959590(A1) 申请公布日期 1999.11.25
申请号 WO1999US10426 申请日期 1999.05.13
申请人 SEPRACOR INC.;YELLE, WILLIAM, E. 发明人 YELLE, WILLIAM, E.
分类号 A61K31/505;A61K31/519;A61K31/675;(IPC1-7):A61K31/505 主分类号 A61K31/505
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