| 发明名称 |
Synthesis of bisindolylmaleimides |
| 摘要 |
The present invention provides for the reaction of optionally substituted indole-3-acetamides with optionally substituted methyl indole-3-glyoxyl reagent to prepare potent PKC inhibitors. The reaction is a very efficient and robust macrocyclization methodology.
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| 申请公布号 |
US5990319(A) |
申请公布日期 |
1999.11.23 |
| 申请号 |
US19970917052 |
申请日期 |
1997.08.22 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
FAUL, MARGARET MARY;WINNEROSKI, JR., LEONARD LARRY |
| 分类号 |
C07D403/14;C07D405/14;C07D498/04;C07D498/22;(IPC1-7):C07D403/14;C07D498/14 |
主分类号 |
C07D403/14 |
| 代理机构 |
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| 主权项 |
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