Selective process for the deacylation of acylated compounds

摘要

PCT No. PCT/EP96/03495 Sec. 371 Date Apr. 23, 1997 Sec. 102(e) Date Apr. 23, 1997 PCT Filed Aug. 5, 1996 PCT Pub. No. WO97/06204 PCT Pub. Date Feb. 20, 1997The invention provides a simple and selective method for the deacylation of 4-acylated statins during the preparation of statins from a fermentation broth, more specifically a reduction of impurities from the process, by increasing the pH of the fermentation broth.