发明名称 Selective modulation of processes mediated by retinoid X receptors, and compounds useful therefor
摘要 In accordance with the present invention, ligands have been discovered which selectively bind retinoid X receptors. Such ligands can be used for the selective modulation of retinoid X receptor mediated processes. In a further aspect of the present invention, there are provided pharmaceutical compositions comprising a pharmaceutically acceptable vehicle containing at least one of the above-described selective ligands. Such compositions are useful, for example, for the treatment of a variety of retinoid X receptor mediated disease states.
申请公布号 US5990163(A) 申请公布日期 1999.11.23
申请号 US19950372218 申请日期 1995.01.13
申请人 THE SALK INSTITUTE FOR BIOLOGICAL STUDIES 发明人 EVANS, RONALD M.;MANGELSDORF, DAVID J.;HEYMAN, RICHARD A.;BOEHM, MARCUS F.;HARMON, MARGARET A.
分类号 A61K31/201;A61K31/202;A61K31/231;A61K31/232;(IPC1-7):A61K31/20;A61K31/23;A61K31/335 主分类号 A61K31/201
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