发明名称 |
Selective modulation of processes mediated by retinoid X receptors, and compounds useful therefor |
摘要 |
In accordance with the present invention, ligands have been discovered which selectively bind retinoid X receptors. Such ligands can be used for the selective modulation of retinoid X receptor mediated processes. In a further aspect of the present invention, there are provided pharmaceutical compositions comprising a pharmaceutically acceptable vehicle containing at least one of the above-described selective ligands. Such compositions are useful, for example, for the treatment of a variety of retinoid X receptor mediated disease states.
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申请公布号 |
US5990163(A) |
申请公布日期 |
1999.11.23 |
申请号 |
US19950372218 |
申请日期 |
1995.01.13 |
申请人 |
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES |
发明人 |
EVANS, RONALD M.;MANGELSDORF, DAVID J.;HEYMAN, RICHARD A.;BOEHM, MARCUS F.;HARMON, MARGARET A. |
分类号 |
A61K31/201;A61K31/202;A61K31/231;A61K31/232;(IPC1-7):A61K31/20;A61K31/23;A61K31/335 |
主分类号 |
A61K31/201 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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