发明名称 |
Use of steroidal alkaloid derivatives as inhibitors of hedgehog signaling pathways |
摘要 |
The present invention makes available assays and reagents inhibiting paracrine and/or autocrine signals produced by a hedgehog protein or aberrant activation of a hedgehog signal transduction pathway, e.g., which involve the use of a steroidal alkaloid or other small molecule. |
申请公布号 |
AU3486099(A) |
申请公布日期 |
1999.11.01 |
申请号 |
AU19990034860 |
申请日期 |
1999.04.09 |
申请人 |
JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE |
发明人 |
PHILIP A BEACHY;MICHAEL K. COOPER;JEFFREY A PORTER |
分类号 |
A61K31/56;A61K31/00;A61K31/4355;A61K31/58;A61P17/00;A61P35/00;A61P43/00;C07J69/00;C07J71/00 |
主分类号 |
A61K31/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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