| 发明名称 |
RAPID DETECTION OF ANTIBIOTIC RESISTANCE IN MYCOBACTERIUM TUBERCULOSIS. |
| 摘要 |
Multidrug resistant strains of Mycobacterium tuberculosis represent a considerable threat to public health worldwide. Resistance to isoniazid (INH), rifampicin or analogues thereof, or streptomycin, i.e. key components of anti-tuberculosis regimens, need frequently to be detected. The invention involves the detection of a mutation in either the katG gene (isoniazid resistance), the rpoB gene (rifampicin resistance) or rpsL gene (streptomycin resistance). |
| 申请公布号 |
GR3030479(T3) |
申请公布日期 |
1999.10.29 |
| 申请号 |
GR19990401553T |
申请日期 |
1999.06.10 |
| 申请人 |
INSTITUT PASTEUR;MEDICAL RESEARCH COUNCIL;ASSISTANCE PUBLIQUE, HOPITAUX DE PARIS;UNIVERSITE PIERRE ET MARIE CURIE;UNIVERSITE DE BERNE |
发明人 |
HEYM, BEATE;COLE, STEWART;YOUNG, DOUGLAS;ZHANG, YING;HONORE, NADINE;TELENTI, AMALIO;BODMER, THOMAS |
| 分类号 |
C12N15/09;C12N9/08;C12Q1/18;C12Q1/68;C12R1/32;G01N33/15;G01N33/50 |
主分类号 |
C12N15/09 |
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