发明名称 PRO-DRUG CONJUGATES FOR THE TREATMENT OF STROKE AND OTHER ISCHAEMIC CONDITIONS
摘要 A prodrug represented by the Formula (I): A - X - B, wherein A comprises a carrier that selectively effects release of B at hypoxic sites in the brain; X comprises a cleavable linker; and B comprises at least one active moiety of a therapeutic agent for the treatment of stroke or other ischaemic conditions.
申请公布号 WO9953908(A2) 申请公布日期 1999.10.28
申请号 WO1999GB01220 申请日期 1999.04.21
申请人 UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED;COTTERILL, ANN, SHERIDAN 发明人 COTTERILL, ANN, SHERIDAN
分类号 A61K31/00;A61K47/48 主分类号 A61K31/00
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