摘要 |
New substituted pyridines can be prepared by reduction of pyridines which are substituted by a ketone radical, and subsequent hydrolysis, cyclization or hydrogenation. The new compounds can be used as active compounds in medicaments, particularly for inhibiting HMG-CoA reductase, for inhibiting cholesterol biosynthesis or for the treatment of hyperlipoproteinaemia, lipoproteinaemia or arteriosclerosis.
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申请人 |
ANGERBAUER, ROLF;FEY, PETER;HUEBSCH, WALTER;SCHMIDT, DELF;PETZINNA, DIETER;PHILIPPS, THOMAS;THOMAS, GUENTER;BISCHOFF, HILMAR |
发明人 |
ANGERBAUER, ROLF;FEY, PETER;HUBSCH, WALTER;SCHMIDT, DELF;PETZINNA, DIETER;PHILIPPS, THOMAS;THOMAS, GUENTER;BISCHOFF, HILMAR |