发明名称 |
Method for detecting the presence of protein C antibody in a fluid sample |
摘要 |
The present invention describes polypeptides and anti-peptide antibodies capable of inhibiting serine protease enzymatic activity. In particular, polypeptides and anti-peptide antibodies derived from the blood coagulation serine proteases Factor VIIa, Factor IXa, Factor Xa, Factor XIa, thrombin and plasma kallikrein are described that are capable of inhibiting coagulation. The polypeptide and antibody are useful in methods and systems for inhibiting serine proteases, and particularly for inhibiting blood coagulation processes mediated by serine proteases in vitro or in a human patient.
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申请公布号 |
US5968751(A) |
申请公布日期 |
1999.10.19 |
申请号 |
US19970955471 |
申请日期 |
1997.10.21 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
GRIFFIN, JOHN H.;MESTERS, ROLF M. |
分类号 |
A61K38/00;C07K14/755;C07K16/40;C12N9/64;(IPC1-7):G01N33/53;G01N33/536 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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