发明名称 |
DEVICE FOR THE TRANSDERMAL DELIVERY OF DICLOFENAC |
摘要 |
The present invention provides a pressure sensitive skin adhesive comprising : (a) a copolymer of one or more alkyl(meth)acrylates containing 4 to 12 carbo n atoms in the alkyl group and one or more hydrophilic monomers; (b) a mixture of penetration enhancers comprising: (i) an alkyl ester of an aliphatic monocarboxylic acid containing 1 to 5 carbon atoms in the alkyl group; (ii) an alkyl pyrrolidone and (iii) an alkane polyol; (c) a therapeutically effectiv e amount of diclofenac or a pharmaceutically acceptable salt thereof. Further provided is a transdermal drug delivery device containing the pressure sensitive skin adhesive.
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申请公布号 |
CA2325400(A1) |
申请公布日期 |
1999.10.14 |
申请号 |
CA19992325400 |
申请日期 |
1999.03.29 |
申请人 |
MINNESOTA MINING AND MANUFACTURING COMPANY |
发明人 |
COORS, CARSTEN;EFFING, JOCHEM J.;BECKER, ANJA N. |
分类号 |
A61K9/70;A61K31/196;A61K47/10;A61K47/14;A61K47/22;A61K47/34;A61P29/00;A61P31/04;(IPC1-7):A61K9/70;A61K47/00;A61K31/195;A61K47/32 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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