发明名称 Treatment of central nervous system disorders with selective estrogen receptor modulators.
摘要 The present invention provides a method of treating depression, mood swings, or Alzheimer's disease in a patient in need of such treatment by administering a selective estrogen receptor modulating compound of the formula in which R1 and R2 are independently hydroxy and alkoxy of one to four carbon atoms; and R3 and R4 are independently methyl or ethyl, or R3 and R4, taken together with the nitrogen atom to which they are attached, form a pyrrolidino, methyl-pyrrolidino, dimethylpyrrolidino, piperidino, morpholino, or hexamethyleneimino ring.
申请公布号 ZA9802877(B) 申请公布日期 1999.10.04
申请号 ZA19980002877 申请日期 1998.04.03
申请人 ELI LILLY AND COMPANY 发明人 KELLY RENEE BALES;HENRY UHLMAN BRYANT;STEVEN MARC PAUL;MARY PATRICIA KNADLER
分类号 C07D333/64;A61K31/381;A61K31/4025;A61K31/4535;A61K31/5377;A61K31/55;A61P25/24;A61P25/28 主分类号 C07D333/64
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