| 摘要 |
PCT No. PCT/FR96/01401 Sec. 371 Date Feb. 4, 1998 Sec. 102(e) Date Feb. 4, 1998 PCT Filed Sep. 12, 1996 PCT Pub. No. WO97/10238 PCT Pub. Date Mar. 20, 1997Compounds of formula (I) in which A represents a 4-(thieno[3,2-c] pyridin-4-yl)-1-piperazinyl or 4-(4-fluorobenzoyl)-1-piperidyl group, R1 and R2 each represent, independently of one another, either a hydrogen or halogen atom, or an amino, hydroxyl, nitro, cyano, (C1-C6)alkyl, (C1-C6)alkoxy, trifluoromethyl, trifluoromethoxy or -COOH group, a group -COOR4, a -CONH2 group or a group -CONHR4, -CONR4R5, -SR4, -SO2R4, -NHCOR4, -NHS02R4 or -N(R4)2, where R4 and R5 are each a (C1-C4)alkyl group, R3 represents either a hydrogen atom, or a (C1-C4)alkyl group, or a group -(CH2)OH, -(CH2)pNH2, -(CH2)nCOOH, -(CH2)nCOOR4, -(CH2)nCONH2, -(CH2)nCONHOH, -(CH2)pSH, -(CH2)nSO3H, -(CH2)nSO2NH2, -(CH2)nSO2NHR4, -(CH2)nSO2NH4R5, -(CH2)nCONHR4, -(CH2)nCONR4R5, -(CH2)pNHSO2R4, -(CH2)pNHCOR4 or -(CH2)pOCOR4, where R4 and R5 are each a (C1-C4)alkyl group, n is equal to 1, 2, 3 or 4, p is equal to 2, 3 or 4 and m is equal to 2, 3 or 4. use in therapy.
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