Substituted 3, 3-diamino-2-propenenitriles, their preparation and use

摘要

Substituted cyanoenamines of the formula I wherein Z, R1, R2 and R3 are defined in the description, compositions thereof and methods for preparing the compounds are disclosed. The compounds are useful in the treatment of diseases of the central nervous system, the cardiovascular system, the pulmonary system, the gastrointestinal system and the endocrinologic system.