发明名称 |
Fremgangsmåte ved utvinning av höyren vWF eller faktor VIII/v-kompleks |
摘要 |
<p>A method for purifying factor VIII/vWF complex or free vWF by immunoaffinity chromatography in a form suitable for use as a medicament. Factor VIII/vWF complex or free vWF is recovered from an immunoaffinity adsorbent by using an eluting agent containing a zwitterionic species. The presence of the zwitterionic species allows for the use of mild conditions throughout the preparation, facilitating retention of molecular integrity, activity, and incorporation of the recovered proteins into pharmaceutical preparations without the need for additional stabilizers or preservatives.</p> |
申请公布号 |
NO994084(D0) |
申请公布日期 |
1999.08.24 |
申请号 |
NO19990004084 |
申请日期 |
1999.08.24 |
申请人 |
BAXTER AG |
发明人 |
MITTERER, ARTUR;FIEDLER, CHRISTIAN;FISCHER, BERNHARD;DORNER, FRIEDRICH;EIBL, JOHANN |
分类号 |
A61K38/36;A61K38/00;A61K38/43;A61P7/04;A61P43/00;C07K1/22;C07K14/755;(IPC1-7):C07K |
主分类号 |
A61K38/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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