| 发明名称 |
Hybrid botulinal neurotoxins |
| 摘要 |
A hybrid botulinal neurotoxin is disclosed. In one embodiment, the neurotoxin comprises a combination of a botulinal neurotoxin heavy chain and light chain, wherein the light chain and heavy chain are not of the same serotype. A method for creating hybrid neurotoxins comprised of different functional domains is also disclosed.
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| 申请公布号 |
US5939070(A) |
申请公布日期 |
1999.08.17 |
| 申请号 |
US19960739477 |
申请日期 |
1996.10.28 |
| 申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
JOHNSON, ERIC A.;GOODNOUGH, MICHAEL C.;BRADSHAW, MARITE |
| 分类号 |
A61K39/00;A61K47/48;C07K14/33;(IPC1-7):A61K39/385;A61K39/08;C12P21/06;C12N9/52 |
主分类号 |
A61K39/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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