| 发明名称 |
Isoxazoline, isothiazoline and pyrazoline factor Xa inhibitors |
| 摘要 |
Isoxazolines, isothiazolines and pyrazolines which are inhibitors of Factor Xa, pharmaceutical compositions containing these compounds, and methods of using these compounds as anticoagulant agents for treatment and prevention of thromboembolic disorders. The compounds can be represented by the formula: where X is O, S or NR15.
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| 申请公布号 |
US5939418(A) |
申请公布日期 |
1999.08.17 |
| 申请号 |
US19960768908 |
申请日期 |
1996.12.17 |
| 申请人 |
THE DUPONT MERCK PHARMACEUTICAL COMPANY |
发明人 |
QUAN, MIMI LIFEN;WITYAK, JOHN;GALEMMO, JR., ROBERT ANTHONY;STOUTEN, PETRUS F. W.;PRUITT, JAMES RUSSELL;PINTO, DONALD J. P. |
| 分类号 |
C07D261/04;C07D413/06;C07D413/12;C07D498/10;(IPC1-7):A61K31/505;A61K31/42 |
主分类号 |
C07D261/04 |
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