发明名称 |
Bactericidal factor in human airway surface fluid and uses thereof |
摘要 |
A bactericidal factor isolated from the surface fluid of airway epithelial cells and uses therefore is described. The bactericidal factor is characterized as having the following features: a) a molecular weight of less than 10 kd; b) heat stable; c) broad spectrum activity including gram positive and gram negative bacteria, fungi, and methicillin resistant Staphylococcus; and d) decreased antimicrobial activity in increasing salt concentration.
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申请公布号 |
US5939393(A) |
申请公布日期 |
1999.08.17 |
申请号 |
US19970840876 |
申请日期 |
1997.04.17 |
申请人 |
UNIVERSITY OF IOWA RESEARCH FOUNDATION |
发明人 |
WELSH, MICHAEL J.;SMITH, JEFFREY J.;TRAVIS, SUE M.;GREENBERG, EVERETT P. |
分类号 |
A01N63/02;A61K38/00;A61K38/17;C07K14/47;(IPC1-7):A61K38/00;A61K38/02;A01N37/18 |
主分类号 |
A01N63/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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