SULFONAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND UTILIZATION THEREOF

摘要

Compounds represented by general formula (I) or salts thereof and prodrugs of the same which have an inhibitory effect on activated blood coagulation factor X and thus are useful as anticoagulating agents. In formula (I), R<1> represents a hydrocarbyl or heterocyclic group each optionally substituted; the ring A represents a divalent nitrogen-containing heterocycle group optionally further substituted; X' represents optionally substituted alkylene; Y represents an optionally substituted divalent cyclic group; X represents a bond or optionally substituted alkylene; and Z represents (1) optionally substituted amino, (2) optionally substituted imidoyl, or (3) an optionally substituted nitrogen-containing heterocyclic group.