IMMUNO-MODULATING PREPARATION CONTAINING INTERLEUKIN-1 AND METHOD FOR PREPARING THE SAME

摘要

The present invention relates to a preparation which is a mixture comprising human serum-albumin and interleukin-1beta in a weight ratio of 20-60:1. This preparation may also contain lactose in a dose of between 1 and 3 mg for 1 mu g of preparation. As shown by experiments, this preparation is capable of stimulating leukopoiesis in conditions where it is strongly inhibited by a toxic leukopenia, including a febrile neutropenia, related to the use of separate cytostatics or combinations thereof when treating malignant tumours. This preparation has an efficient therapeutic action in the case of leukopenia induced by the action of ionising radiation, and also has radio-protection properties. This preparation has an immuno-stimulating action which is strongly expressed, and can be used for treating secondary immuno-deficiency conditions due to surgical interventions or traumas.