Composição formulação farmacêutica uso e processo para preparação de um composto e para tratamento de uma condição onde a trombina seja necessária

摘要

There is provided compounds of formula I, R<1>O(O)C-CH2-(R)Cgl-Aze-Pab-R<2> wherein R<1> and R<2> have meanings given in the description, which are useful as prodrugs of inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (eg thrombosis) or as anticoagulants.