发明名称 |
METHOD AND COMPOSITION OF AN ORAL PREPARATION OF ITRACONAZOLE |
摘要 |
The present invention relates to a method and composition of an oral preparation of itraconazole, an excellent azole antifungal drug. More particularly, it relates to an oral preparation of itraconazole having improved bioavailability, which is prepared by following steps of: i) dissolving itraconazole and hydrophilic polymer with solvent, ii) spray-drying said mixture, and iii) preparing the solid dispersions for oral preparation. The solid dispersions prepared in this invention may be useful in preparing tablets, granules and other oral dosage forms.
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申请公布号 |
CA2317106(A1) |
申请公布日期 |
1999.07.08 |
申请号 |
CA19982317106 |
申请日期 |
1998.12.17 |
申请人 |
CHOONGWAE PHARMA CORPORATION |
发明人 |
PARK, JONG WOO;HONG, JI WOONG;LEE, SANG HEON;LEE, KYU HYUN;KIM, KYE HYUN;JUNG, JAE YOUNG |
分类号 |
A61K9/14;A61K9/16;A61K9/20;A61K9/48;A61K31/496;A61K47/32;A61P31/10;(IPC1-7):A61K31/495 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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