发明名称 |
Hydrate of 5-{4-{2- (n-methyl-n- (2-pyridil)amino) ethoxy}benzyl} thiazolidine-2, 4-dione maleic acid salt |
摘要 |
A hydrate of 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione, maleic acid salt, characterised in that it: (i) comprises water in the range of from 0.2 to 1.1% w/w ; and (ii) provides an infra red spectrum containing peaks at 764 and 579 cm<SUP>-1</SUP>; and/or (iii) provides an X-ray powder diffraction (XRPD) pattern substantially as set out in Figure II; a process for the preparation of such a compound, a pharmaceutical composition containing such a compound and the use of such a compound or composition in medicine. |
申请公布号 |
AU2272399(A) |
申请公布日期 |
1999.07.05 |
申请号 |
AU19990022723 |
申请日期 |
1998.12.14 |
申请人 |
SMITHKLINE BEECHAM PLC |
发明人 |
PAUL DAVID JAMES BLACKLER;DAVID C. LEE;MICHAEL JOHN SASSE |
分类号 |
A61K31/4427;A61K31/4439;A61P3/10;C07D417/12 |
主分类号 |
A61K31/4427 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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