TYPE 2 HELPER T CELL-SELECTIVE IMMUNE RESPONSE SUPPRESSORS

摘要

Type 2 helper T cell-selective immune response suppressors, immune response modulators and antiallergic agents containing purine derivatives represented by general formula (I) as the active ingredient wherein R<2> represents H or hydrocarbyl; R<6> represents amino mono- or disubstituted by OH, NH2 or hydrocarbyl; R<8> represents OH, SH, acyloxy or hydrocarbyloxycarbonyloxy; and R<9> represents hydrocarbyl, provided that in the hydrocarbyl represented by R<2> and R<9>, -CH2- not directly bonded to the purine skeleton may be replaced by CO, SO2, O or S and C-H not directly bonded to the purine skeleton may be replaced by N, C-halogeno or C-CN.