发明名称 METHOD TO DETECT MRIT AND BCL-2 OR CASPASE ASSOCIATION ALTERATIONS
摘要 The invention provides a method of identifiying an effective agent that alters the association of a Bcl-2 polypeptide with an MACH Related Inducer of Toxicity (MRIT) polypeptide by contacting a Bcl-2 family polypeptide and an MRIT polypeptide with an agent under conditions that allow said Bcl-2 family polypeptide to associate with said MRIT polypeptide; and detecting an altered association of said Bcl-2 family polypeptide and said MRIT polypeptide.
申请公布号 WO9918230(A3) 申请公布日期 1999.06.17
申请号 WO1998US21132 申请日期 1998.10.07
申请人 UNIVERSITY OF WASHINGTON 发明人 CHAUDHARY, PREET, M.
分类号 C07K14/47;C12Q1/37;G01N33/68 主分类号 C07K14/47
代理机构 代理人
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