发明名称 |
Oral salmon calcitonin pharmaceutical products |
摘要 |
Bioavailability of salmon calcitonin to be administered orally is enhanced by a pharmaceutical composition providing targeted release of the peptide to the intestine, together with an absorption enhancer and a sufficient amount of a pH-lowering agent to lower local intestinal pH. Specific concentrations and classes of these agents are disclosed to account for the particular characteristics of salmon calcitonin.
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申请公布号 |
US5912014(A) |
申请公布日期 |
1999.06.15 |
申请号 |
US19960616250 |
申请日期 |
1996.03.15 |
申请人 |
UNIGENE LABORATORIES, INC. |
发明人 |
STERN, WILLIAM;GILLIGAN, JAMES P. |
分类号 |
A61K9/00;A61F2/00;A61K9/16;A61K9/28;A61K9/30;A61K9/36;A61K9/48;A61K9/50;A61K9/52;A61K9/62;A61K38/00;A61K38/11;A61K38/23;A61K38/28;A61K47/18;A61K47/24;A61K47/28;A61P19/08;A61P19/10;(IPC1-7):A61K9/28 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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