| 发明名称 |
COMPLEX SPECIFIC ANTIBODIES, METHOD OF PREPARATION AND USES THEREOF |
| 摘要 |
Methods are provided that utilize a naive antibody library for preparing monoclonal antibodies directed against an antigen complex. In particular, method s are provided for preparing antibodies that show specificity for the PSA-ACT complex (prostate-specific antigen complexed to anti-chymotrypsin) as opposed to the fre e subunits of the complex. Antibodies prepared by these methods are provided.
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| 申请公布号 |
CA2253633(A1) |
申请公布日期 |
1999.06.03 |
| 申请号 |
CA19982253633 |
申请日期 |
1998.12.01 |
| 申请人 |
BOEHRINGER MANNHEIM CORPORATION |
发明人 |
SAWYER, JAYMIE R.;WINTER, GREGORY P.;MAHONEY, WALTER C. |
| 分类号 |
G01N33/531;C07K16/00;C07K16/40;C12N15/09;C12P21/08;G01N33/574;(IPC1-7):C07K16/40;C07K16/38;C07K16/46;G01N33/554;G01N33/573 |
主分类号 |
G01N33/531 |
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