| 摘要 |
A composite having a small particle diameter and composed of a water-soluble carboxypolysaccharide and a magnetic iron oxide having a core diameter ranging from about 2 to about 7 nm, wherein the overall diameter ranges from about 10 to about 50 nm, the ratio of the overall diameter to the core diameter is about 15 or less, and the T2 relaxation capacity ranges from about 10 to about 150 (mM.sec)<-><1>. The composite is reduced in toxicity and side effects and is useful as iron preparation, X-ray contrast medium, MRI contrast medium, reagent for blood stream measurement, drug carrier, and so forth in the fields of medicine, biology and engineering. <IMAGE> |
| 申请人 |
MEITO SANGYO K.K., NAGOYA, AICHI, JP |
发明人 |
HASEGAWA, MASAKATSU 29, DOUTOKUSHIN-MACHI 5-CHOME, NAGOYA-SHI AICHI 457, JP;ITO, YOSHIO 203-3, YAMAHANA-CHO, NAGOYA-SHI AICHI 466, JP;YAMADA, HISATO 24, TENDO SHIGO-CHO, AICHI 470-03, JP;NAGAE, HIDEO 8-7, HIGASHINO-CHO 2-CHOME, AICHI 486, JP;TOZAWA, NAHOKO 170-4, HIGASHIYAMA-CHO 1-CHOME, AICHI 489, JP;HINO, YUKARI 88, TAISHI 3-CHOME, NAGOYA-SHI AICHI 458, JP;KITO, KYOJI 701, BENTENGAOKA, NAGOYA-SHI AICHI 463, JP;HOKUKOKU, SHUSABURO 55, WAKABADAI 8-CHOME, GIFU 509-02, JP;LAWACZECK, RUDIGER, D-13503 BERLIN, DE;EBERT, WOLFGANG, D-12203 BERLIN, DE;PFEFFERER, DETLEF, D-13505 BERLIN, DE;WAGNER, SUSANNE, D-10781 BERLIN, DE;KRESSE, MAYK, D-10711 BERLIN, DE |
