COMPOSITIONS AND METHODS TO PREVENT TURKEY ENTERITIS

摘要

A preselected DNA segment encoding turkey enteric coronavirus S1 polypeptide is provided. Also provided are methods to inhibit or prevent spiking mortality of turkeys (SMT). Further provided are immunogenic compositions comprising cell culture adapted coronaviruses. A method to detect the presence of turkey enteric coronavirus or antibodies thereto in a sample derived from a bird or mammal is also provided.