发明名称 NOVEL REOVIRUS-DERIVED PROTEINS, NUCLEIC ACIDS ENCODING SAME, AND USES THEREFOR
摘要 In accordance with the present invention, viral proteins that are responsible for membrane fusion and syncytium formation induced by three different fusogenic orthoreoviruses, i.e., avian reoviruses (ARV), Nelson Bay virus (NBV), and Baboon Reovirus (BRV), have been identified. The genes encoding these proteins have been cloned and sequenced; functional analysis thereof indicates that expression of these proteins in transfected cells results in cell-cell fusion.
申请公布号 CA2310213(A1) 申请公布日期 1999.05.20
申请号 CA19982310213 申请日期 1998.11.06
申请人 DALHOUSIE UNIVERSITY 发明人 DUNCAN, ROY
分类号 C12N15/09;A61K9/127;A61K38/00;A61K45/00;C07K14/14;C07K16/10;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N5/12;C12N5/16;C12N15/46;C12P21/02;C12P21/08;C12Q1/68;(IPC1-7):C12N15/46;C12N15/02;C12N15/88 主分类号 C12N15/09
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