摘要 |
PROBLEM TO BE SOLVED: To find a pharmaceutical that effectively inhibits the activation of NF-κB. SOLUTION: This NF-κB activation inhibitor is a compound that is represented by the general formula [R<1> and R<2> are each an amino group which may be protected; R<3> and R<4> are identical or different and represent each a lower alkyl or a lower alkoxy; n is 2 or 3], or its salts. Typically, this inhibitor contains, as an active ingredient, bis(2-amino-4-methoxyphenyl) disulfide or bis(2-amino-4-methoxyphenyl) trisulfide or their salts.
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