发明名称 |
NOVEL FORMULATION FOR USE IN PAIN MANAGEMENT |
摘要 |
The present invention is directed to a novel topical pharmaceutical water-in-oil composition in form of a cream or lotion, comprising i) 2-50 % of a local anaesthetic in oil form in the final composition, or two or more local anaesthetics forming an oil when mixed together, effective to produce a topical anaesthetic effect upon administration; ii) 2-50 % of a water-in-oil emulsifier, effective to produce an emulsion of the desired viscosity; and iii) 2-96 % water. Optionally the composition may contain up to 20 % of pharmaceutically acceptable stabilizers or penetration enhancers. This novel pharmaceutical composition is useful in therapy, particularly for the treatment of pain.
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申请公布号 |
CA2309122(A1) |
申请公布日期 |
1999.05.14 |
申请号 |
CA19982309122 |
申请日期 |
1998.10.27 |
申请人 |
ASTRAZENECA AKTIEBOLAG |
发明人 |
WELIN-BERGER, KATAYOUN;BERGENSTAHL, BJORN |
分类号 |
C07D211/60;A61K9/00;A61K9/06;A61K9/107;A61K31/138;A61K31/167;A61K31/245;A61K31/445;A61K31/451;A61K47/14;A61K47/34;A61K47/44;A61P23/02;C07D211/64;(IPC1-7):A61K9/107;A61K31/135 |
主分类号 |
C07D211/60 |
代理机构 |
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主权项 |
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