| 摘要 |
The D-homo-9,10-secocholesta-23-yne-3,25-diol derivatives of formula (I) wherein the dotted C-C bond in the D-ring is optional, C(R,R) is CH2 or C=CH2, R<1> is H, F or OH, R<2> and R<3> are each independently C1-4-alkyl or CF3, or C(R<2>,R<3>) is C3-6-cycloalkyl, are useful in the treatment of vitamin D dependent disorders, such as psoriasis, leukemia; acne and seborrhoic dermatitis; osteoporosis, hyperparathyroidism accompanying renal failure; and multiple sclerosis.
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