ZUBEREITUNG VON PHARMAZEUTISCHEN UND ANDEREN MATRIXSYSTEMEN DURCH AUFLÖSUNG IN FESTEM ZUSTAND
摘要
A method is disclosed for preparing pharmaceutical and other matrix systems that comprises solidifying a matrix composition dissolved or dispersed in a first solvent and subsequently contacting the solidified matrix with a second solvent that is substantially miscible with the first solvent at a temperature lower than the solidification point of the first solvent, the matrix components being substantially insoluble in the second solvent, whereby the first solvent is substantially removed resulting in a usable matrix.
申请公布号
DE69032976(D1)
申请公布日期
1999.04.08
申请号
DE1990632976
申请日期
1990.12.11
申请人
JANSSEN PHARMACEUTICA INC., TITUSVILLE, N.J., US
发明人
GOLE, DILIP, J., ANN ARBOR, MI 48105, US;LEVINSON, R., SAUL, CHESTERFIELD, MISSOURI 63005, US;DAVIES, J., DESMOND, GROSSE POINT FARMS, MI 48236, US;CARBONE, JAMES, BELLEVILLE, MI 48111, US