摘要 |
<p>Novel 2-oxo-1-azetidine sulfonic acid derivatives which are potent inhibitors of bacterial β-lactamases, particularly against class C β-lactamases. Pharmaceutical compositions contain these compounds, and optionally also a β-lactam antibiotic. The compounds and compositions can be used to inhibit β-lactamase inactivation, and for the treatment of bacterial infections.</p> |