Purified and isolated nucleic acid molecules are provided which encode lactoferrin receptor proteins of Moraxella, such as M. catarrhalis, or a fragment or an analog of the lactoferrin receptor protein. The nucleic acid sequence may be used to produce recombinant lactoferrin receptor proteins Lbp1, Lbp2 or ORF3 of the strain of Moraxella free of other proteins of the Moraxella strain for purposes of diagnostics and medical treatment. Furthermore, the nucleic acid molecule may be used in the diagnosis of infection.
申请公布号
WO9855606(A3)
申请公布日期
1999.03.04
申请号
WO1998CA00544
申请日期
1998.06.02
申请人
CONNAUGHT LABORATORIES LIMITED;LOOSMORE, SHEENA, M.;DU, RUN-PAN;WANG, QUIJUN;YANG, YAN-PING;KLEIN, MICHEL, H.
发明人
LOOSMORE, SHEENA, M.;DU, RUN-PAN;WANG, QUIJUN;YANG, YAN-PING;KLEIN, MICHEL, H.