摘要 |
<p>PCT No. PCT/US97/05509 Sec. 371 Date Sep. 25, 1997 Sec. 102(e) Date Sep. 25, 1997 PCT Filed Apr. 1, 1997 PCT Pub. No. WO97/37689 PCT Pub. Date Oct. 16, 1997A pharmaceutical composition has an acid salt of a sympathomimetic amine; and a denaturant of (i) at least one gum or viscosity modifier, and (ii) at least one surfactant, wherein the gum or viscosity modifier and the surfactant are present in amounts sufficient to have a denaturing effect on the sympathomimetic amine without significantly compromising the release of the sympathomimetic amine from the composition.</p> |