| 发明名称 |
SUBSTITUTED ALKANOHYDROXAMIC ACIDS AND METHOD OF REDUCING TNF.ALPHA. LEVELS |
| 摘要 |
Imido and amido substituted alkanohydroxamic acids reduce the levels of TNF.alpha. and inhibit phosphodiesterase in a mammal. A typical embodiment is 3-(3-cyclopentyloxy-4-methoxyphenyl)-N-hydroxy-3-phthalimidopropionamide.
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| 申请公布号 |
CA2295295(A1) |
申请公布日期 |
1999.02.11 |
| 申请号 |
CA19982295295 |
申请日期 |
1998.07.30 |
| 申请人 |
CELGENE CORPORATION |
发明人 |
MULLER, GEORGE W.;MAN, HON-WAH |
| 分类号 |
C07D491/056;A61K31/4015;A61K31/403;A61K31/4035;A61K31/407;A61K31/425;A61K31/4465;A61K31/45;A61K31/513;A61P1/02;A61P1/04;A61P11/00;A61P11/06;A61P19/00;A61P19/02;A61P19/10;A61P27/02;A61P29/00;A61P31/12;A61P35/00;A61P35/04;A61P43/00;C07D207/327;C07D209/46;C07D209/48;C07D209/66;C07D275/00;C07D413/04;C07D471/04;C07D487/04;C07D491/04;(IPC1-7):A61K31/40;A61K31/445;A61K31/515 |
主分类号 |
C07D491/056 |
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