Solid pharmaceutical compositions containing (S)-2-(4-isobutylphenyl) propionic acid active ingredient and microcrystalline cellulose and colloidal silica as excipients

摘要

PCT No. PCT/EP95/02010 Sec. 371 Date Nov. 27, 1996 Sec. 102(e) Date Nov. 27, 1996 PCT Filed May 26, 1995 PCT Pub. No. WO95/35104 PCT Pub. Date Dec. 28, 1995The present invention relates to a solid pharmaceutical composition containing (S)-2-(4-isobutylphenyl) propionic acid as active ingredient and it relates to a solid pharmaceutical composition suitable for the preparation of pharmaceutical forms in tablets, sachets and capsules containing (S)-2-(4-isobutylphenyl)-propionic acid as active ingredient. This formulation in tablets contains (S)-Ibupropen, colloidal silica as disintegrating agent, microcrystalline cellulose as diluent and magnesium stearate as lubricant. Tablets are prepared by direct compression of the pharmaceutical composition object of the present invention and may be coated or filmed according to conventional techniques.