发明名称 |
Solid form of administration of isosorbide 5-mononitrate |
摘要 |
A solid form of oral administration of isosorbide 5-mononitrate with a controlled, pH-independent release of the active substance in the gastro-intestinal tract is constituted by a pellet coated with a depot layer and a release prolonging lacquer layer. The lacquer layer contains ethyl cellulose and polymethacrylate in a weight ratio from 3:1 to 3:2. The new form of administration is characterized in that it is less costly to produce.
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申请公布号 |
US5869094(A) |
申请公布日期 |
1999.02.09 |
申请号 |
US19970788295 |
申请日期 |
1997.01.24 |
申请人 |
BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH |
发明人 |
VAN EGMOND, CORNELIA ALIDA MARIA;PULLEN, ANDRE;DE JONG, SIBO WYTSE;DE JONG, ADRIANUS PETRUS;BRON, JAN |
分类号 |
A61K9/28;A61K9/22;A61K9/50;A61K9/52;A61K31/34;A61K47/14;A61K47/32;A61K47/38;(IPC1-7):A61K9/50 |
主分类号 |
A61K9/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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