发明名称 PHOSPHONATED AGENTS AND THEIR ANTIANGIOGENIC AND ANTITUMORIGENIC USE
摘要 The present invention relates to novel phosphonic acid substituted agents and their pharmaceutical compositions. The novel agents are defined by the following formula: (P-Yn1)m1-Q-K-(Q2-(Yn2-P)m2)j wherein Y is -OCO-, NR1CO- or CON(R1)R2-; Q1 and Q2 are substituted or unsubstituted aryl groups; K is H, -NHCONH-, NHCS-NH, -NHCO-R3- or -NHCSR3-CSNH-; provided when K is H, j is 0; j is 0, 1, 2; n1 and n2 are independently 0, 1 or 2; and m1 and m2 are independently an integer from 1-4.
申请公布号 WO9905148(A1) 申请公布日期 1999.02.04
申请号 WO1998US15470 申请日期 1998.07.24
申请人 UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 发明人 COLLINS, DELWOOD, C.;GAGLIARDI, ANTONIO, R.;NICKEL, PETER
分类号 C07F9/38 主分类号 C07F9/38
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