| 发明名称 |
MERCAPTO- OR ACYLTHIO-TRIFLUOROMETHYL AMIDE DERIVATIVES AND METHOD OF THEIR PREPARATION |
| 摘要 |
<p>Disclosed are mercapto- or acylthio-trifluoromethyl amide derivatives of the general formula (I) wherein X, Y and Z denote the groups stated in the Description, such as neutral endopeptidase inhibitors usable as cardio-vascular agents. There is further disclosed their preparation that is processed by addition of a compound of the general formula H2N-X or hydrochloride salt thereof to the activated form of carboxylic acid of the general formula (II).</p> |
| 申请公布号 |
SK279617(B6) |
申请公布日期 |
1999.01.11 |
| 申请号 |
SK19910000765 |
申请日期 |
1991.03.21 |
| 申请人 |
DELANEY NORMA G.;ROVNYAK GEORGE C.;LOOTS MELANIE |
发明人 |
DELANEY NORMA G.;ROVNYAK GEORGE C.;LOOTS MELANIE |
| 分类号 |
A61K31/16;A61K31/00;A61K31/095;A61K31/165;A61K31/195;A61K31/198;A61K31/215;A61K31/22;A61K31/265;A61K31/34;A61K31/341;A61K31/343;A61K31/35;A61K31/38;A61K31/381;A61K31/40;A61K31/403;A61K31/4035;A61K31/404;A61K31/41;A61K31/435;A61P1/00;A61P1/16;A61P7/10;A61P9/00;A61P9/08;A61P9/10;A61P9/12;A61P13/00;A61P13/02;A61P15/00;A61P43/00;C07C323/60;C07C327/32;C07D207/09;C07D207/16;C07D207/32;C07D207/337;C07D209/14;C07D209/20;C07D209/44;C07D213/36;C07D213/40;C07D213/56;C07D213/59;C07D213/79;C07D215/48;C07D217/26;C07D231/38;C07D231/56;C07D235/16;C07D257/04;C07D307/66;C07D307/81;C07D333/20;C07D403/06;C07K5/06;(IPC1-7):C07C323/60 |
主分类号 |
A61K31/16 |
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