| 发明名称 |
SPECIFIC MAGNETOSOME, METHOD FOR THE PRODUCTION AND USE THEREOF |
| 摘要 |
The invention relates to specific magnetosomes consisting of a magnetic iron oxide magnetite Fe3O4 monocrystal with a diameter </=45 nm and a phospholipid membrane surrounding said crystal, in addition to magnetoliposomes which can be obtained from said magnetosomes by liposomal encapsulation. The invention further relates to a method for the production and use thereof as NMR contrast agents, in purging (removal of pathogenic cells), as diagnostic agents for tumoral diseases or in lymphography, for inflammatory processes, for multiple sclerosis, Alzheimer disease, Parkinson's disease and as therapeutic agents. |
| 申请公布号 |
WO9840049(A3) |
申请公布日期 |
1999.01.07 |
| 申请号 |
WO1998DE00668 |
申请日期 |
1998.03.06 |
| 申请人 |
MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN;MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. BERLIN;BAEUERLEIN, EDMUND;SCHUELER, DIRK;RESZKA, REGINA;PAEUSER, SABINE |
发明人 |
BAEUERLEIN, EDMUND;SCHUELER, DIRK;RESZKA, REGINA;PAEUSER, SABINE |
| 分类号 |
C12P3/00;A61K9/127;A61K33/26;A61K39/395;A61K41/00;A61K47/48;A61K48/00;A61K49/00;A61K49/18;A61N2/06;A61P3/00;A61P29/00;A61P35/00;C01G49/08;C12N1/20;C12N15/88 |
主分类号 |
C12P3/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
