发明名称 |
CD154 BLOCKADE THERAPY FOR PANCREATIC ISLET TISSUE TRANSPLANTATION |
摘要 |
<p>Methods and compositions for inhibiting rejection of insulin-producing tissue in a graft recipient, as well as methods and compositions for prolonging graft survival or function; for reversing graft rejection or restoring function of an impaired graft; and, for inducing immunological tolerance to grafted, insulin-producing tissue. The present methods and compositions are suitable for treatment or prophylaxis of defects in metabolic control of blood glucose homeostasis, including defects manifested as diabetes melitus (DM).</p> |
申请公布号 |
CA2294154(A1) |
申请公布日期 |
1998.12.30 |
申请号 |
CA19982294154 |
申请日期 |
1998.06.19 |
申请人 |
BIOGEN, INC.;UNIVERSITY OF MIAMI |
发明人 |
THOMAS, DAVID W.;BURKLY, LINDA;KENYON, NORMA S.;RICORDI, CAMILLO |
分类号 |
A61K39/395;A61K35/28;A61K38/00;A61P3/08;A61P3/10;A61P37/06;C07K16/28;(IPC1-7):A61K39/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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