发明名称 Ternary ligand complexes useful as radiopharmaceuticals
摘要 The present invention provides novel radiopharmaceuticals useful for imaging the heart, brain, lungs, liver or kidneys, kits useful for preparing the radiopharmaceuticals, and methods of imaging the heart, brain, lungs, liver or kidneys in a patient in need of such imaging. The radiopharmaceuticals are comprised of technetium or rhenium radionuclide complexes of a ternary ligand system: one hydrazido or diazenido ligand, one aminoalcohol ligand, and one pi-acid ligand selected from phosphines, arsines, and imine nitrogen-containing heterocycles. The radiopharmaceuticals have the formula, ML1L2L3, wherein the variables are as defined herein.
申请公布号 AU7802098(A) 申请公布日期 1998.12.30
申请号 AU19980078020 申请日期 1998.05.28
申请人 THE DU PONT MERCK PHARMACEUTICAL COMPANY 发明人 SHAUNG LIU
分类号 A61K51/00;A61K51/04;A61P35/00;C07D213/77;C07D213/82;C07F9/50;C07F13/00 主分类号 A61K51/00
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