发明名称 |
17-spiromethylene steroids |
摘要 |
The invention relates to a steroid derivative which steroidal skeleton is bound at carbon atom 17 to a spiromethylene ring of the formula: <IMAGE> wherein Ra and Rb are independently selected from the group consisting of hydrogen, methyl, and halogen; m is 1 or 2; and the asterisk denotes carbon atom 2 of the spiromethylene ring which is carbon atom 17 (or carbon atom 17 alpha of a homosteroid skeleton) of the steroid. The steroids have progestational or antiprogestational activity.
|
申请公布号 |
US5854235(A) |
申请公布日期 |
1998.12.29 |
申请号 |
US19970962798 |
申请日期 |
1997.11.03 |
申请人 |
AKZO NOBEL N.V. |
发明人 |
HAMERSMA, JOHANNES ANTONIUS MARIA;ORLEMANS, EVERARDUS OTTO MARIA;REWINKEL, JOHANNES BERNARDUS MARIA |
分类号 |
A61K31/58;A01N43/80;A61P5/24;C07J5/00;C07J21/00;C07J31/00;C07J41/00;C07J43/00;C07J51/00;C07J53/00;C07J63/00;C07J71/00;(IPC1-7):A61K31/58 |
主分类号 |
A61K31/58 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|